I've been in your shoes a few times for various reasons. For example, I once sold most of my US silver. Spot was around 40 bucks back then and I needed the money more than I needed the coins. I didnt own anything rare, few of us do. You can replace most anything you have.
So trim trim trim that collection. Sell trade or give away anything outside your core collection. Dont be afraid to let go. Remember this is your hobby. Dont let it control you. You can always rebuild.
Only you can say what you'll keep. For me, the few times I started over, I hung on to my Canadian coins, especially some silver dollars and large cents. Dont know why. I love the designs and the coins werent worth enough to sell. So I kept them. What's your focus?